April 29, 2021
5 college members on the College of Washington are amongst 120 new members and 30 worldwide members elected to the Nationwide Academy of Sciences. The brand new members embrace 59 ladies, essentially the most chosen in a single 12 months, in accordance with an April 26 announcement by the academy.
The 5 new members from the UW are:
Karlin, who holds the Invoice and Melinda Gates Chair within the Paul G. Allen College of Laptop Science & Engineering, works in theoretical pc science. She earned a bachelor’s diploma in utilized arithmetic and a doctoral diploma in pc science at Stanford College. Earlier than becoming a member of the UW college in 1994, she labored for 5 years at what was then the Digital Gear Company’s Methods Analysis Heart. On the UW, Karlin is a member of the Theory of Computation group within the Paul G. Allen College of Laptop Science & Engineering. Her analysis facilities on designing and analyzing sure forms of algorithms — resembling probabilistic algorithms, which incorporate a level of probability or randomness, and on-line algorithms, which might deal with enter delivered in a step-by-step method. Karlin additionally works in algorithmic sport concept, a area that merges algorithm design with concerns of strategic conduct. Her research have additionally intersected different disciplines, together with economics and information mining. In 2016, she was elected to the American Academy of Arts and Sciences.
Klevit, who holds the Edmond H. Fischer-Washington Analysis Basis Endowed Chair in Biochemistry, research molecular recognition, significantly how proteins work together in human illnesses. Considered one of her laboratory’s efforts is to check the massive, multifunctional protein produced by the BRCA1 gene, which when carrying sure mutations can predispose individuals to inherited types of breast and different cancers. Klevit’s group additionally research small warmth shock proteins, that are implicated in sure muscle losing illnesses and a few cancers. Cells manufacture these beneath stress as a consequence of warmth, lack of oxygen and adjustments in acidity or alkalinity. Klevit’s staff makes use of totally different nuclear magnetic resonance approaches to know the construction and features of those proteins, which have been tough to unravel. Klevit and her staff additionally use NMR to check a sensor enzyme important to bacterial virulence. This enzyme responds to environmental alerts, such because the presence of antimicrobials, by turning on or off genes concerned in an infection. Klevit received a Rhodes Scholarship in 1978 — a 12 months after this system was open to ladies — to check at Oxford College, the place she earned a doctoral diploma in chemistry in 1981.
LeVeque, who earned a doctoral diploma in pc science at Stanford College, got here to the UW in 1985 after postdoctoral positions at New York College and the College of California, Los Angeles. Whereas at UW, he was additionally briefly a college member at ETH Zürich. LeVeque’s mathematical analysis has spanned quite a lot of matters associated to numerical algorithms for fixing the partial differential equations that mannequin wave propagation phenomena. He has additionally developed in depth open supply software program primarily based on this analysis. LeVeque’s mathematical and computational research have impacted fields starting from biophysics to astrophysics. A lot of his current work has centered on modeling geological hazards, significantly tsunamis, and he’s a part of an interdisciplinary staff performing hazard assessments for the coast of the Pacific Northwest. LeVeque has additionally taught extensively and authored a number of textbooks. He’s an information science fellow on the UW eScience Institute, and was beforehand elected a fellow of each the American Mathematical Society and the Society of Industrial and Utilized Arithmetic.
Theriot, who holds the Benjamin D. Corridor Endowed Chair in Primary Life Sciences and is an investigator with the Howard Hughes Medical Institute, got here to the UW in 2018 after 21 years as a college member at Stanford College. She earned a doctoral diploma in cell biology from the College of California, San Francisco, and was a fellow on the Whitehead Institute for Biomedical Analysis earlier than heading to Stanford. Theriot’s analysis facilities on the dynamic world inside cells. Her work explores how cells self-organize to carry out duties — like change form, transfer, reply to stimuli, and shuttle gadgets via their interiors. Theriot has investigated these questions in quite a lot of organic settings, resembling how white blood cells crawl via our our bodies and engulf invading microbes, how fish pores and skin heals wounds, and the way the bacterial pathogen Listeria monocytogenes rearranges the proteins of the human cell’s “skeleton.” She employs many forms of experimental approaches, from mathematical modeling to video-based analyses of mobile actions. Theriot has acquired fellowships from the John D. and Catherine T. MacArthur Basis and the David and Lucile Packard Basis.
Wong, who’s chair of the Division of Organic Construction, research how the circuitries of nerve cells develop, break and reassemble. Her analysis mannequin is the vertebrate retina, the a part of the attention that receives gentle and converts it into alerts despatched to the mind. Her staff applies a variety of strategies to analyze the construction and connectivity of nerve cells in regular and altered retinas, resembling monitoring adjustments in zebrafish retinal neurons from the time they first seem till they kind circuits and investigating how retinal neurons rewire throughout mobile regeneration. As well as, Wong’s staff constructs detailed connectivity maps of neurons within the internal and outer retina, and researches how the transmission of nerve alerts helps set up and preserve connectivity between retinal neurons. She is collaborating to check how the eyes encode a visible scene. Wong earned her doctoral diploma from the Australian Nationwide College, and serves on the steering committee for the Nationwide Eye Institute’s Audacious Goals Initiative for Regenerative Medicine, which seeks to revive imaginative and prescient misplaced from harm to the retina and optic nerve.
Julie Overbaugh, a professor of human biology and of public well being sciences on the Fred Hutchinson Cancer Research Center, was additionally elected to the academy. Overbaugh is an affiliate UW professor of microbiology.
With these new members, the Nationwide Academy of Sciences now has 2,461 lively members, in addition to 511 worldwide members, who’re nonvoting and maintain citizenship outdoors of the U.S.
Tag(s): Anna Karlin • awards • College of Arts & Sciences • College of Engineering • Department of Applied Mathematics • Department of Biochemistry • Department of Biological Structure • Department of Biology • Julie Theriot • Paul G. Allen School of Computer Science & Engineering • Rachel Klevit • Rachel Wong • Randy LeVeque • School of Medicine